Last month at Carolines in New York City, Bob Saget and a handful of his comedian friends, including Jeffrey Ross, Colin Quinn, James Smith and Jeff Garlin, came together to raise money for Scleroderma research at an event dubbed Cool Comedy, Hot Cuisine.

The Scleroderma Research Foundation describes the condition as “a rheumatic disease of the connective tissues. It is a chronic, degenerative disorder accompanied by widespread vascular deterioration and tissue loss. Scleroderma can be disfiguring, debilitating, and deadly. In the most serious cases, the disease causes severe damage and severe complications for the body’s digestive, respiratory, and circulatory systems.” Saget lost a sister to the disease; he’s on the board of directors at the foundation.

The good news is that this one event — also attended by Ashley and Mary-Kate Olsen, Saget’s former Full House co-stars, raised $525,000 for research. Saget and friends are constantly trying to raise awareness of the disease which is said to affect 300,000 Americans. If you want to donate online go here. For more info on the disease, check out the foundation’s official site. While you’re thinking about donating, check out the video below, wherein Danny Lobell chatted with Saget on behalf of Punchline Magazine on the red carpet of the event.